Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013173 | 0.87 | PARP10 (0.62) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL9430917 | 0.86 | PARP10 (0.58) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL8471656 | 0.86 | PARP10 (0.58) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL2089763 | 0.82 | PARP10 (0.73) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL12310925 | 0.80 | ALDH1A1 (0.59) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL1733690 | 0.80 | PARP10 (0.60) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL68570 | 0.80 | ALOX5 (0.69) | PARP10ALDH1A1SMN1; SMN2MAOBNPC1 | |
| Ammonia Solution, Strong SCHEMBL23291159 | 0.78 | ALDH1A1 (0.58) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL1193236 | 0.78 | PARP10 (0.59) | PARP10ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL11996178 | 0.78 | PARP10 (0.63) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |
| US-4110457-A | HYPOTENSIVE, CARDIOACTIVE | CIBA-GEIGY CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |