Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.61 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11248134 | 0.97 | ALOX5 (0.66) | ALOX5MAOBPTGS1PTGS2NR4A1 | |
| SCHEMBL1066614 | 0.86 | FFAR1 (0.70) | ALOX5MAOBPTGS1PTGS2NR4A1 | |
| SCHEMBL1928563 | 0.85 | MAOB (0.71) | MAOBNR4A2FFAR1ALDH1A1NPC1 | |
| SCHEMBL13599952 | 0.85 | MEN1 (0.63) | ALOX5MAOBPTGS1PTGS2NR4A1 | |
| SCHEMBL4222632 | 0.84 | FFAR1 (0.68) | ALOX5MAOBPTGS1PTGS2NR4A1 | |
| Ammonia Solution, Strong SCHEMBL27788257 | 0.84 | FFAR1 (0.68) | ALOX5MAOBPTGS1PTGS2NR4A1 | |
| SCHEMBL20425306 | 0.84 | MAOB (0.70) | ALOX5MAOBPTGS1PTGS2NR4A1 | |
| Hydrochloric Acid SCHEMBL10622121 | 0.84 | FFAR1 (0.68) | ALOX5MAOBPTGS1PTGS2NR4A1 | |
| SCHEMBL10861821 | 0.84 | PKM (0.58) | ALOX5FFAR1L3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL9632286 | 0.83 | MAOB (0.53) | ALOX5MAOBL3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239471-A1 | SYNTHESIS OF COELENTERAZINE | ALLY BANK, AS COLLATERAL AGENT | 2020-07-30 | — | — | US | claimed |
| CN-110627704-B | Preparation method of bazedoxifene | 艾瑞吉瑞股份公司 | 2024-02-23 | — | — | CN | disclosed |
| US-11078200-B2 | Synthesis of coelenterazine | INTERNATIONAL PAPER COMPANY (US) | 2021-08-03 | — | — | US | disclosed |
| US-10925840-B2 | Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200239471-A1 | SYNTHESIS OF COELENTERAZINE | ALLY BANK, AS COLLATERAL AGENT | 2020-07-30 | — | — | US | disclosed |
| US-20200197332-A1 | USE OF FENOTEROL AND FENOTEROL ANALOGUES IN THE TREATMENT OF GLIOBLASTOMAS AND ASTROCYTOMAS | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-06-25 | — | — | US | disclosed |
| US-10617654-B2 | Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-04-14 | — | — | US | disclosed |
| US-10562843-B2 | Preparation of (R,R)-fenoterol and (R,R)- or (R,S)-fenoterol analogues and their use in treating congestive heart failure | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-02-18 | — | — | US | disclosed |
| CN-110627704-A | Preparation method of bazedoxifene | 艾瑞吉瑞股份公司 | 2019-12-31 | — | — | CN | disclosed |
| US-20190248732-A1 | PREPARATION OF (R,R)-FENOTEROL AND (R,R)- OR (R,S)-FENOTEROL ANALOGUES AND THEIR USE IN TREATING CONGESTIVE HEART FAILURE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) | 2019-08-15 | — | — | US | disclosed |
| EP-0051917-B1 | BENZOFURAN ETHANOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1986-02-19 | — | — | EP | disclosed |
| EP-0070134-B1 | SECONDARY PHENYL ETHANOL AMINES AND THEIR PHARMACEUTICAL USE | BEECHAM GROUP PLC (GB) | 1985-11-13 | — | — | EP | disclosed |
| EP-0066351-B1 | ARYLETHANOL AMINE DERIVATIVES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1985-06-26 | — | — | EP | disclosed |
| US-4432993-A | 2-(2-BENZOFURANYL)ETHANOLAMINE | BEECHAM GROUP LIMITED (GB) | 1984-02-21 | — | — | US | disclosed |
| EP-0070134-A1 | Secondary phenyl ethanol amines and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1983-01-19 | — | — | EP | disclosed |
| EP-0023385-B1 | ETHANAMINE DERIVATIVES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1982-12-15 | — | — | EP | disclosed |
| EP-0066351-A1 | Arylethanol amine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1982-12-08 | — | — | EP | disclosed |
| US-4338333-A | ANTIOBESITY, HYPOGLYCEMIC | BEECHAM GROUP LIMITED (GB) | 1982-07-06 | — | — | US | disclosed |
| EP-0051917-A1 | Benzofuran ethanolamine derivatives, processes for their preparation, and their use in medicine | BEECHAM GROUP PLC (GB) | 1982-05-19 | — | — | EP | disclosed |
| EP-0023385-A1 | Ethanamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10617654-B2 | Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas | ADRB2, ADRB1, ADRA2A | ALOX5 989/4885MAOB 1275/4885PTGS1 506/4885 |
| US-10562843-B2 | Preparation of (R,R)-fenoterol and (R,R)- or (R,S)-fenoterol analogues and their use in treating congestive heart failure | ADRB2, ADRB1, ADRB3 | ALOX5 914/4885MAOB 1288/4885PTGS1 617/4885 |
| US-20200197332-A1 | USE OF FENOTEROL AND FENOTEROL ANALOGUES IN THE TREATMENT OF GLIOBLASTOMAS AND ASTROCYTOMAS | ADRB2, ADRB1, ADRA2A | ALOX5 989/4885MAOB 1275/4885PTGS1 506/4885 |
| US-20190248732-A1 | PREPARATION OF (R,R)-FENOTEROL AND (R,R)- OR (R,S)-FENOTEROL ANALOGUES AND THEIR USE IN TREATING CONGESTIVE HEART FAILURE | ADRB2, ADRB1, ADRB3 | ALOX5 914/4885MAOB 1288/4885PTGS1 617/4885 |
| US-10925840-B2 | Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas | ADRB2, ADRB1, ADRA2A | ALOX5 989/4885MAOB 1275/4885PTGS1 506/4885 |
| US-11078200-B2 | Synthesis of coelenterazine | ACHE, UROD, DDT | ALOX5 804/4885MAOB 291/4885PTGS1 1910/4885 |
| US-20200239471-A1 | SYNTHESIS OF COELENTERAZINE | ACHE, UROD, DDT | ALOX5 804/4885MAOB 291/4885PTGS1 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.