Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032874 | 0.83 | NR4A1 (0.52) | HDAC8HDAC6MCL1ACMSDMEN1 | |
| SCHEMBL11436575 | 0.80 | NR4A1 (0.52) | HDAC8HDAC6MCL1ACMSDMEN1 | |
| SCHEMBL250471 | 0.79 | HSD17B10 (0.56) | HDAC8HDAC6MCL1ACMSDMEN1 | |
| SCHEMBL1460367 | 0.78 | KDM4E (0.46) | HDAC8HDAC6MCL1ACMSDMEN1 | |
| SCHEMBL21835145 | 0.77 | HDAC8 (0.66) | HDAC8HDAC6MCL1ACMSDALDH1A1 | |
| SCHEMBL30698051 | 0.77 | HDAC8 (0.66) | HDAC8HDAC6MCL1ACMSDALDH1A1 | |
| SCHEMBL18153975 | 0.76 | CES2 (0.50) | HDAC8MCL1MEN1KMT2AALDH1A1 | |
| SCHEMBL27806445 | 0.76 | RORC (0.54) | HDAC8HDAC6MCL1ACMSDMEN1 | |
| SCHEMBL11751512 | 0.75 | TYMS (0.43) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL11752525 | 0.75 | TYMS (0.43) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145938-A | PREPARATION OF POLY(ARYLENE ETHER KETONES) | RAYCHEM LIMITED (GB) | 1992-09-08 | — | — | US | disclosed |