Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.77 |
| ▸ | NPC1 | O15118 | 10/20 | 0.77 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630176 | 0.85 | NPC1 (0.60) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 | |
| SCHEMBL6815343 | 0.84 | RAB9A (0.79) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 | |
| SCHEMBL3561578 | 0.84 | RAB9A (0.79) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 | |
| SCHEMBL3563799 | 0.82 | KMT2A (0.79) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 | |
| SCHEMBL864179 | 0.82 | RAB9A (0.74) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 | |
| SCHEMBL16763420 | 0.81 | KMT2A (1.00) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 | |
| SCHEMBL19313566 | 0.79 | KMT2A (0.69) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 | |
| SCHEMBL16763369 | 0.78 | KMT2A (0.72) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 | |
| SCHEMBL18884363 | 0.77 | HTT (0.69) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 | |
| SCHEMBL9630150 | 0.77 | HTT (0.47) | RAB9ANPC1HSP90AA1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |