Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962571 | 0.83 | TSHR (0.47) | LMNARAB9ASMN1; SMN2ALDH1A1MMP12 | |
| SCHEMBL3526490 | 0.82 | USP5 (0.64) | USP5L3MBTL1KMT2ANR4A2CYP1A2 | |
| SCHEMBL11174352 | 0.82 | KMT2A (0.52) | L3MBTL1KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL25146524 | 0.78 | LMNA (0.62) | USP5L3MBTL1KMT2ANR4A2CYP1A2 | |
| SCHEMBL8155949 | 0.78 | SMN1; SMN2 (0.50) | L3MBTL1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11235329 | 0.78 | ACACB (0.60) | USP5L3MBTL1KMT2ASIGMAR1 | |
| SCHEMBL5617244 | 0.77 | ALDH1A1 (0.52) | CYP1A2LMNARAB9AALDH1A1SIGMAR1 | |
| SCHEMBL9028692 | 0.77 | ALDH1A1 (0.52) | CYP1A2LMNARAB9AALDH1A1SIGMAR1 | |
| SCHEMBL3505882 | 0.77 | ALDH1A1 (0.52) | CYP1A2LMNARAB9AALDH1A1SIGMAR1 | |
| SCHEMBL11239470 | 0.77 | USP5 (0.53) | USP5L3MBTL1KMT2ANR4A2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |