Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TLR3 | O15455 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536176 | 0.82 | TTPA (0.51) | TTPAKMT2AMAPTMEN1PDE4A | |
| SCHEMBL9531581 | 0.81 | TLR3 (0.41) | PKMKMT2AMAPTPOLBMAOB | |
| SCHEMBL8177483 | 0.80 | KMT2A (0.39) | TTPAPKMKMT2AMAPTPOLB | |
| SCHEMBL10636395 | 0.80 | CYP3A4 (0.49) | KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL8172698 | 0.79 | MEN1 (0.36) | TTPAKMT2AMEN1PDE4APDE3A | |
| SCHEMBL8490863 | 0.75 | KMT2A (0.39) | TTPAKMT2AMAPTPOLBMAOB | |
| SCHEMBL10641788 | 0.75 | MEN1 (0.53) | TTPAKMT2AMAPTMEN1PDE4A | |
| SCHEMBL9632161 | 0.75 | TTPA (0.39) | TTPAPKMKMT2AMAPTPOLB | |
| SCHEMBL10636293 | 0.74 | TTPA (0.49) | TTPAKMT2AMAPTMAOBMEN1 | |
| SCHEMBL9531634 | 0.73 | TLR3 (0.47) | PKMKMT2AMAPTPOLBTLR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |