Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177483 | 0.91 | KMT2A (0.39) | TTPAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9632620 | 0.86 | MEN1 (0.33) | TTPAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9631440 | 0.86 | KMT2A (0.38) | TTPAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9630744 | 0.81 | MEN1 (0.46) | TTPAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL7536176 | 0.79 | TTPA (0.51) | TTPAKMT2AMEN1MAPT | |
| SCHEMBL9630971 | 0.79 | PPARG (0.31) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7125937 | 0.78 | MEN1 (0.36) | TTPAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7123640 | 0.77 | GAA (0.44) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL10636293 | 0.77 | TTPA (0.49) | TTPAKMT2AMEN1MAPTMAOB | |
| SCHEMBL9531639 | 0.77 | KMT2A (0.42) | KMT2ANPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |