Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.35 |
| ▸ | TTPA | P49638 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639032 | 0.87 | KMT2A (0.47) | MEN1KMT2AMAPTTDP1PSEN1 | |
| SCHEMBL9630613 | 0.86 | TTPA (0.48) | GABRA5MEN1KMT2AMAPTTDP1 | |
| SCHEMBL9631272 | 0.86 | MAPT (0.48) | MEN1KMT2AMAPTTDP1TTPA | |
| SCHEMBL9075912 | 0.79 | PSEN1 (0.40) | MEN1KMT2AMAPTTDP1PSEN1 | |
| SCHEMBL15854991 | 0.77 | PSEN1 (0.43) | MEN1KMT2AMAPTTDP1PSEN1 | |
| SCHEMBL9631048 | 0.77 | MAPT (0.48) | MEN1KMT2AMAPTTDP1PSEN1 | |
| SCHEMBL9221402 | 0.73 | PSEN1 (0.37) | MEN1KMT2AMAPTPSEN1TTPA | |
| SCHEMBL7536176 | 0.72 | TTPA (0.51) | MEN1KMT2AMAPTTDP1PSEN1 | |
| SCHEMBL9633187 | 0.72 | MEN1 (0.49) | MEN1KMT2AMAPTTDP1PSEN1 | |
| SCHEMBL9632542 | 0.72 | PSEN1 (0.45) | MEN1KMT2AMAPTPSEN1TTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |