SCHEMBL9631480

SCHEMBL9631480

CC1CN(CCCC[Si](C)(C)Cc2ccc(Cl)cc2)CC(C)O1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
KMT2A Q03164 2/20 0.49
POLB P06746 2/20 0.49
SIGMAR1 Q99720 4/20 0.47
EBP Q15125 1/20 0.44
KDM4E B2RXH2 6/20 0.43
TDP1 Q9NUW8 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9633375 0.96 POLB (0.50) ALDH1A1KMT2APOLBSIGMAR1EBP
SCHEMBL9631832 0.84 SIGMAR1 (0.53) ALDH1A1KMT2APOLBSIGMAR1EBP
SCHEMBL9419062 0.82 SIGMAR1 (0.63) ALDH1A1KMT2APOLBSIGMAR1EBP
SCHEMBL9631471 0.77 ALDH1A1 (0.52) ALDH1A1KMT2APOLBSIGMAR1EBP
SCHEMBL9631870 0.76 CYP2A13 (0.49) ALDH1A1KMT2ASIGMAR1EBPKDM4E
SCHEMBL9631442 0.75 KDM4E (0.60) ALDH1A1KMT2APOLBSIGMAR1EBP
SCHEMBL9631874 0.72 POLB (0.35) ALDH1A1KMT2APOLBKDM4ESMN1; SMN2
SCHEMBL9631876 0.71 ALDH1A1 (0.52) ALDH1A1KMT2APOLBSIGMAR1EBP
SCHEMBL9631473 0.71 SIGMAR1 (0.50) ALDH1A1KMT2APOLBSIGMAR1EBP
SCHEMBL9449910 0.69 CCR1 (0.52) ALDH1A1KMT2APOLBSIGMAR1EBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP claimed
US-4927812-A FUNGICIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-05-22 US claimed
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO claimed
EP-0313353-A1 Morpholinyl silanes and use for control of plant diseases caused by fungi DOWELANCO (US) 1989-04-26 EP claimed
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP disclosed
US-4927812-A FUNGICIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-05-22 US disclosed
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO disclosed
EP-0313353-A1 Morpholinyl silanes and use for control of plant diseases caused by fungi DOWELANCO (US) 1989-04-26 EP disclosed