SCHEMBL9631442

SCHEMBL9631442

CC1CN(CCC[Si](C)(C)Cc2ccccc2Cl)CC(C)O1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.60
HTT P42858 1/20 0.60
CYP2A13 Q16696 1/20 0.51
LMNA P02545 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 4/20 0.42
SIGMAR1 Q99720 5/20 0.40
KMT2A Q03164 2/20 0.40
EBP Q15125 1/20 0.40
POLB P06746 1/20 0.40
DRD2 P14416 1/20 0.39
HTR2A P28223 1/20 0.39
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631870 0.86 CYP2A13 (0.49) KDM4EHTTCYP2A13LMNATDP1
SCHEMBL9633375 0.79 POLB (0.50) KDM4EHTTLMNATDP1ALDH1A1
SCHEMBL7372983 0.76 KDM4E (1.00) KDM4EHTTCYP2A13LMNATDP1
SCHEMBL9631480 0.75 ALDH1A1 (0.49) KDM4ELMNATDP1ALDH1A1SIGMAR1
SCHEMBL9631832 0.73 SIGMAR1 (0.53) KDM4EHTTLMNATDP1ALDH1A1
SCHEMBL9632634 0.72 KDM4E (0.50) KDM4EHTTLMNATDP1ALDH1A1
SCHEMBL9631471 0.70 ALDH1A1 (0.52) KDM4EHTTLMNATDP1ALDH1A1
SCHEMBL9631134 0.70 SIGMAR1 (0.51) KDM4EHTTCYP2A13LMNATDP1
SCHEMBL9631437 0.70 KDM4E (0.58) KDM4EHTTCYP2A13LMNATDP1
SCHEMBL13850015 0.68 CYP2A13 (1.00) KDM4EHTTCYP2A13LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP claimed
US-4927812-A FUNGICIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-05-22 US claimed
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP disclosed
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO disclosed
EP-0313353-A1 Morpholinyl silanes and use for control of plant diseases caused by fungi DOWELANCO (US) 1989-04-26 EP disclosed