Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909110 | 0.81 | PSEN1 (0.40) | MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL388601 | 0.78 | MTNR1A (0.54) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL10225789 | 0.76 | MTNR1A (0.51) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL11896109 | 0.75 | MTNR1A (0.62) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8765995 | 0.75 | MTNR1A (0.62) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL629488 | 0.75 | MTNR1A (0.61) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL9629764 | 0.75 | MTNR1B (0.46) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL23343811 | 0.74 | DRD2 (0.54) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL11669272 | 0.74 | DRD2 (0.54) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL3961628 | 0.74 | DRD2 (0.54) | MTNR1AMTNR1BCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213080-B1 | HYDROGENATED PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-05-20 | — | — | EP | disclosed |
| EP-0213080-A2 | Hydrogenated pyridine derivatives | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | disclosed |