Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379001 | 0.65 | MAOB (0.41) | MAOBMAOANPY1R | |
| SCHEMBL6901583 | 0.64 | KMT2A (0.63) | — | |
| SCHEMBL2173396 | 0.61 | MAOB (0.41) | MAOBMAOAHSD11B1 | |
| SCHEMBL23672519 | 0.60 | MAOB (0.39) | MAOBMAOAHSD11B1 | |
| SCHEMBL23595712 | 0.59 | SLC6A3 (0.61) | — | |
| SCHEMBL121601 | 0.59 | HSD11B1 (0.46) | MAOBMAOAHSD11B1 | |
| SCHEMBL4087444 | 0.58 | MAOB (0.46) | MAOBMAOAHSD11B1 | |
| SCHEMBL23293520 | 0.58 | SLC6A9 (0.43) | — | |
| SCHEMBL13221434 | 0.57 | MAOB (0.50) | MAOBMAOAHSD11B1POLB | |
| SCHEMBL426911 | 0.57 | SLC6A9 (0.45) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |