Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10635866 | 0.86 | PPARG (0.35) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL10639044 | 0.85 | L3MBTL1 (0.38) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL10639162 | 0.84 | PPARG (0.41) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL9632908 | 0.84 | DDB1 (0.34) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL10892586 | 0.82 | PPARG (0.39) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL9630982 | 0.82 | KMT2A (0.36) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL10641941 | 0.79 | PPARG (0.39) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL10640704 | 0.77 | PPARG (0.46) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL9630971 | 0.77 | PPARG (0.31) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL9631020 | 0.77 | PPARG (0.43) | ALDH1A1HPGDHSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |