Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.31 |
| ▸ | HPGD | P15428 | 5/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.31 |
| ▸ | CASP1 | P29466 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10635866 | 0.91 | PPARG (0.35) | PPARGKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9632313 | 0.88 | MEN1 (0.30) | MEN1KMT2APDE4APDE3A | |
| SCHEMBL9631403 | 0.83 | MEN1 (0.42) | MEN1KMT2APDE4APDE3A | |
| SCHEMBL10641941 | 0.82 | PPARG (0.39) | PPARGKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9632620 | 0.82 | MEN1 (0.33) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL10892586 | 0.81 | PPARG (0.39) | PPARGSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7454938 | 0.80 | PPARG (0.49) | PPARGMEN1KMT2APDE4APDE3A | |
| SCHEMBL10635779 | 0.80 | MEN1 (0.39) | PPARGMEN1KMT2APDE4APDE3A | |
| SCHEMBL10639044 | 0.79 | L3MBTL1 (0.38) | PPARGALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9632161 | 0.79 | TTPA (0.39) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |