Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632908 | 0.89 | DDB1 (0.34) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL8177483 | 0.84 | KMT2A (0.39) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL9531639 | 0.82 | KMT2A (0.42) | KMT2ANPC1RAB9AMEN1PTGS2 | |
| SCHEMBL9632055 | 0.82 | KDM4E (0.33) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL8980424 | 0.81 | KMT2A (0.44) | KMT2ANPC1RAB9AMEN1PTGS2 | |
| SCHEMBL9631020 | 0.78 | PPARG (0.43) | KMT2AMEN1MAPTALDH1A1CYP1A2 | |
| SCHEMBL9631939 | 0.77 | MEN1 (0.32) | KMT2AMEN1MAPT | |
| SCHEMBL9632161 | 0.75 | TTPA (0.39) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL655716 | 0.72 | PTGS2 (0.60) | KMT2AMEN1PTGS2MAPTALDH1A1 | |
| SCHEMBL7125937 | 0.72 | MEN1 (0.36) | KMT2AMEN1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |