SCHEMBL9632112

SCHEMBL9632112

CCc1nc2ccccc2cc1C(=O)OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.52
NPC1 O15118 2/20 0.52
KMT2A Q03164 1/20 0.52
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 4/20 0.46
HPGD P15428 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RXFP1 Q9HBX9 2/20 0.44
HTT P42858 2/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.44
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30819462 0.88 KDM4E (0.48) RAB9AKMT2AKDM4EALDH1A1HPGD
SCHEMBL24951256 0.88 KDM4E (0.48) RAB9AKMT2AKDM4EALDH1A1HPGD
SCHEMBL17427768 0.83 IKBKB (0.46) RAB9ANPC1KMT2AKDM4EALDH1A1
SCHEMBL2552834 0.83 GABRP (0.50) RAB9ANPC1KMT2AKDM4EALDH1A1
SCHEMBL17339728 0.81 IKBKB (0.45) RAB9ANPC1KMT2AKDM4EALDH1A1
SCHEMBL4184724 0.80 NPC1 (0.51) RAB9ANPC1KMT2AKDM4EALDH1A1
SCHEMBL68891 0.80 KDM4E (0.51) RAB9AKMT2AKDM4EALDH1A1HPGD
SCHEMBL30201832 0.80 SMN1; SMN2 (0.60) RAB9ANPC1KMT2AKDM4EALDH1A1
SCHEMBL16234345 0.80 KDM4E (0.51) RAB9AKMT2AKDM4EALDH1A1HPGD
SCHEMBL5255504 0.78 IKBKB (0.66) RAB9AKMT2AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101638353-B Method for removing residual metal in organic compounds by using EDTA calcium disodium salts as chelons in liquid phase LIANYUNGANG JINKANG PHARMACEUTICAL TECHNOLOGY CO LTD 2013-03-20 CN disclosed
CN-101638353-A Method for removing residual metal in organic compounds by using EDTA calcium disodium salts as chelons in liquid phase LIANYUNGANG JINKANG PHARMACEUT 2010-02-03 CN disclosed
US-5098462-A Herbicides SANDOZ LTD. (CH) 1992-03-24 US disclosed
US-5098466-A Herbicides SANDOZ LTD. (CH) 1992-03-24 US disclosed