Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.33 |
| ▸ | GAA | P10253 | 10/20 | 0.33 |
| ▸ | HPGD | P15428 | 9/20 | 0.33 |
| ▸ | CASP1 | P29466 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.33 |
| ▸ | GLA | P06280 | 6/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10640498 | 0.88 | KDM4E (0.39) | CYP1A1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9633233 | 0.87 | RECQL (0.37) | CYP1A1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9631003 | 0.82 | KDM4E (0.34) | CYP1A1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9630958 | 0.80 | KDM4E (0.37) | CYP1A1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9632290 | 0.79 | ALDH1A1 (0.44) | CYP1A1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL10640285 | 0.76 | KDM4E (0.39) | CYP1A1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9533181 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL10639871 | 0.74 | CYP3A4 (0.39) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL9632121 | 0.71 | ALDH1A1 (0.41) | CYP1A1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9631957 | 0.71 | AKT1 (0.37) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |