Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632121 | 0.83 | ALDH1A1 (0.41) | MAPTALDH1A1CYP1A2CYP3A4POLB | |
| SCHEMBL9630813 | 0.83 | TLR3 (0.40) | TLR3MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9633267 | 0.81 | TLR3 (0.48) | TLR3MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9631366 | 0.79 | TLR3 (0.42) | TLR3MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9533164 | 0.76 | TLR3 (0.48) | TLR3MAPTALDH1A1POLBPKM | |
| SCHEMBL9531581 | 0.76 | TLR3 (0.41) | TLR3MAPTALDH1A1CYP3A4POLB | |
| SCHEMBL9632290 | 0.74 | ALDH1A1 (0.44) | MAPTALDH1A1CYP1A2CYP3A4POLB | |
| SCHEMBL9531634 | 0.74 | TLR3 (0.47) | TLR3MAPTALDH1A1POLBPKM | |
| SCHEMBL9630958 | 0.72 | KDM4E (0.37) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL9632014 | 0.70 | TLR3 (0.45) | TLR3MAPTALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |