Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.34 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426926 | 0.80 | PARP1 (0.42) | PARP1GRM5PPOXCHEK1GSK3B | |
| SCHEMBL29710128 | 0.77 | GRM5 (0.46) | PARP1GRM5PPOXCHEK1GSK3B | |
| SCHEMBL9279015 | 0.77 | GRM5 (0.46) | PARP1GRM5PPOXCHEK1GSK3B | |
| SCHEMBL28920768 | 0.75 | GRM5 (0.44) | PARP1GRM5PPOXCHEK1GSK3B | |
| SCHEMBL9489040 | 0.74 | GSK3B (0.46) | PARP1CHEK1GSK3BWEE1USP8 | |
| SCHEMBL29704524 | 0.73 | GSK3B (0.45) | PARP1CHEK1GSK3BWEE1USP8 | |
| SCHEMBL28099608 | 0.69 | PARP1 (0.46) | PARP1GRM5PPOXCHEK1GSK3B | |
| SCHEMBL6651902 | 0.68 | TRPV4 (0.48) | EGLN2UPP1AR | |
| Phosphoric Acid SCHEMBL30230307 | 0.68 | GRM5 (0.39) | PARP1GRM5PPOXCHEK1GSK3B | |
| SCHEMBL7943820 | 0.68 | USP8 (0.47) | GRM5PPOXCHEK1GSK3BUPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484381-A1 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |