SCHEMBL9632432

SCHEMBL9632432

Cc1ccc(N(CC(=O)O)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.51
NFE2L2 Q16236 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C19 P33261 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
TRPM8 Q7Z2W7 1/20 0.44
TSHR P16473 1/20 0.43
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
PTGIR P43119 1/20 0.42
PTGDR Q13258 1/20 0.42
PPARG P37231 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL9461781 0.92 KEAP1 (0.44) KEAP1NFE2L2MEN1NPC1RAB9A
SCHEMBL440156 0.88 NPSR1 (0.48) SMN1; SMN2MEN1NPC1RAB9AKMT2A
Water SCHEMBL28256553 0.86 NPSR1 (0.46) SMN1; SMN2MEN1NPC1RAB9AKMT2A
SCHEMBL11339632 0.84 ALDH1A1 (0.49) SMN1; SMN2MEN1NPC1RAB9AKMT2A
SCHEMBL11750937 0.81 KMT2A (0.59) SMN1; SMN2MEN1NPC1RAB9AKMT2A
SCHEMBL5690847 0.81 ALDH1A1 (0.52) SMN1; SMN2NPC1RAB9AKMT2ACYP2C19
SCHEMBL2485185 0.81 SCN9A (0.52) KEAP1NFE2L2KMT2ATSHRMTNR1A
SCHEMBL11341409 0.81 KEAP1 (0.45) KEAP1NFE2L2SMN1; SMN2NPC1RAB9A
SCHEMBL2484595 0.81 CACNA2D1 (0.49) KEAP1NFE2L2SMN1; SMN2NPC1RAB9A
SCHEMBL2485731 0.80 MTNR1A (0.60) KEAP1NFE2L2SMN1; SMN2KMT2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362188-B Synthesis method of alpha-substituted deuterated amino acid ester 广州医科大学 2025-05-20 CN disclosed
CN-117362188-A Synthesis method of alpha-substituted deuterated amino acid ester 广州医科大学 2024-01-09 CN disclosed
EP-0295044-B1 PHOTOINITIATOR AND PHOTOPOLYMERIZABLE COMPOSITION USING THE SAME Hitachi Chemical Co., Ltd. (JP) 1992-04-22 EP disclosed
EP-0295044-A2 Photoinitiator and photopolymerizable composition using the same Hitachi Chemical Co., Ltd. (JP) 1988-12-14 EP disclosed
US-4248677-A ELECTROCHEMICAL REDUCTION OF IMINES TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1981-02-03 US disclosed