Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 5/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632035 | 0.94 | ADRB2 (0.54) | ADRB2DRD2DRD3DRD1DRD4 | |
| SCHEMBL9632729 | 0.93 | ADRB2 (0.51) | ADRB2DRD2DRD3DRD1DRD4 | |
| SCHEMBL9416163 | 0.90 | ADRB2 (0.65) | ADRB2DRD2DRD3DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL9123410 | 0.89 | ADRB2 (0.64) | ADRB2DRD2DRD3DRD1DRD4 | |
| SCHEMBL9633205 | 0.87 | ADRA1A (0.61) | ADRB2DRD2DRD3HTR1ASLC6A4 | |
| SCHEMBL14301033 | 0.85 | ADRA1A (0.70) | ADRB2DRD2DRD3DRD1DRD4 | |
| SCHEMBL9634047 | 0.83 | ADRA1D (0.55) | ADRB2DRD2DRD3HTR1ASLC6A4 | |
| SCHEMBL9632519 | 0.83 | ADRA1D (0.59) | ADRB2DRD2DRD3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL9632456 | 0.82 | ADRA1D (0.58) | ADRB2DRD2DRD3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL9633345 | 0.82 | ADRA1D (0.54) | ADRB2DRD2DRD3HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331943-B1 | PHENOXYETHYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR EXHIBITING EXCELLENT ALPHA-1-BLOCKING ACTIVITY CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4971990-A | HYPOTENSIVE AGENTS, DYSUREA | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0331943-A1 | Phenoxyethylamine derivatives, process for preparing the same, and composition for exhibiting excellent alpha-1-blocking activity containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-09-13 | — | — | EP | disclosed |