Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630717 | 0.86 | PDE10A (0.45) | PDE10AALOX5GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9630746 | 0.84 | PDE10A (0.43) | PDE10AALOX5GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9631884 | 0.80 | PDE10A (0.58) | PDE10AALOX5GPBAR1CYSLTR1 | |
| SCHEMBL9632868 | 0.78 | SMN1; SMN2 (0.49) | ALOX5GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9632136 | 0.76 | PDE10A (0.54) | PDE10AALOX5GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL7008427 | 0.75 | GPBAR1 (0.64) | PDE10AALOX5GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9630560 | 0.75 | PDE10A (0.52) | PDE10AALOX5GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9719811 | 0.73 | GPBAR1 (0.62) | PDE10AALOX5GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL7454127 | 0.73 | CYSLTR1 (0.63) | ALOX5GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL10690965 | 0.72 | CYSLTR1 (0.76) | PDE10AALOX5GPBAR1CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120744-A | For combating diseases susceptible to the action of lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-09 | — | — | US | disclosed |