Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630560 | 0.91 | PDE10A (0.52) | PDE10AADAMTS4ALOX5GPBAR1CYSLTR2 | |
| SCHEMBL9632132 | 0.83 | ADAMTS4 (0.52) | PDE10AADAMTS4ALOX5GPBAR1CYSLTR2 | |
| SCHEMBL9865885 | 0.77 | GPBAR1 (0.57) | PDE10AADAMTS4ALOX5GPBAR1CYSLTR2 | |
| SCHEMBL9866291 | 0.77 | CYSLTR1 (0.52) | PDE10AADAMTS4ALOX5GPBAR1CYSLTR2 | |
| SCHEMBL9632872 | 0.76 | PDE10A (0.48) | PDE10AALOX5GPBAR1CYSLTR2CYSLTR1 | |
| SCHEMBL7008427 | 0.76 | GPBAR1 (0.64) | PDE10AALOX5GPBAR1CYSLTR2CYSLTR1 | |
| SCHEMBL9630717 | 0.76 | PDE10A (0.45) | PDE10AALOX5GPBAR1CYSLTR2CYSLTR1 | |
| SCHEMBL9719811 | 0.74 | GPBAR1 (0.62) | PDE10AALOX5GPBAR1CYSLTR2CYSLTR1 | |
| SCHEMBL9876648 | 0.74 | CYSLTR2 (0.60) | PDE10AADAMTS4ALOX5GPBAR1CYSLTR2 | |
| SCHEMBL9630746 | 0.74 | PDE10A (0.43) | PDE10AALOX5GPBAR1CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120744-A | For combating diseases susceptible to the action of lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-09 | — | — | US | disclosed |