Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HEXA | P06865 | 1/20 | 0.50 |
| ▸ | HEXB | P07686 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631943 | 0.95 | RAB9A (0.60) | RAB9ATSHRNPC1HPGDMAPK1 | |
| SCHEMBL9633218 | 0.88 | RAB9A (0.59) | RAB9ATSHRNPC1HPGDMAPK1 | |
| SCHEMBL9632000 | 0.88 | RAB9A (0.59) | RAB9ATSHRNPC1HPGDMAPK1 | |
| SCHEMBL29227699 | 0.87 | TSHR (0.75) | RAB9ATSHRNPC1HPGDMAPK1 | |
| SCHEMBL30960133 | 0.87 | TSHR (0.75) | RAB9ATSHRNPC1HPGDMAPK1 | |
| SCHEMBL9632462 | 0.87 | RAB9A (0.61) | RAB9ATSHRNPC1HPGDMAPK1 | |
| SCHEMBL6565574 | 0.84 | L3MBTL1 (0.59) | RAB9ATSHRNPC1HPGDMAPK1 | |
| SCHEMBL6567482 | 0.83 | RAB9A (0.62) | RAB9ATSHRNPC1HPGDMAPK1 | |
| SCHEMBL15013524 | 0.82 | RXFP1 (0.64) | RAB9ATSHRNPC1HPGDMAPK1 | |
| SCHEMBL8816740 | 0.82 | TSHR (0.56) | RAB9ATSHRNPC1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331943-B1 | PHENOXYETHYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR EXHIBITING EXCELLENT ALPHA-1-BLOCKING ACTIVITY CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4971990-A | HYPOTENSIVE AGENTS, DYSUREA | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0331943-A1 | Phenoxyethylamine derivatives, process for preparing the same, and composition for exhibiting excellent alpha-1-blocking activity containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-09-13 | — | — | EP | disclosed |