Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631943 | 0.83 | RAB9A (0.60) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL9633041 | 0.83 | RAB9A (0.60) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL6566423 | 0.82 | RAB9A (0.60) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL9632000 | 0.82 | RAB9A (0.59) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL9633218 | 0.82 | RAB9A (0.59) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL9632462 | 0.81 | RAB9A (0.61) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL6565574 | 0.80 | L3MBTL1 (0.59) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL4713152 | 0.80 | ALDH1A1 (0.64) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL11638432 | 0.78 | RAB9A (0.54) | RAB9ANPC1TSHRHPGDALDH1A1 | |
| SCHEMBL1677061 | 0.77 | RAB9A (1.00) | RAB9ANPC1TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135360-B1 | NOVEL 3-ALKOXYBENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICINES FOR TREATING SCHIZOPHRENIA | PF MEDICAMENT (FR) | 2004-03-31 | — | — | EP | disclosed |
| EP-1187824-B1 | NOVEL (2-SUBSTITUTED-5 - 3-THIENYL) -BENZYL]- 2- ( 2-ISOPROPOXY-5-FLUORO] -PHENOXY) -ETHYL] -AMINE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | PF MEDICAMENT (FR) | 2002-11-13 | — | — | EP | disclosed |
| US-6417222-B1 | DRUGS FOR PSYCHOLOGICAL DISORDERS OR COGNITION ACTIVATORS | PIERRE FABRE MEDICAMENT (FR) | 2002-07-09 | — | — | US | disclosed |
| EP-1187824-A2 | NOVEL (2-SUBSTITUTED-5 - 3-THIENYL) -BENZYL]- 2- ( 2-ISOPROPOXY-5-FLUORO] -PHENOXY) -ETHYL] -AMINE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | PIERRE FABRE MEDICAMENT (FR) | 2002-03-20 | — | — | EP | disclosed |
| US-6350913-B1 | AROMATIC AMINE COMPOUNDS | PIERRE FABRE MEDICAMENT (FR) | 2002-02-26 | — | — | US | disclosed |
| EP-1135360-A1 | NOVEL 3-ALKOXYBENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICINES FOR TREATING SCHIZOPHRENIA | PIERRE FABRE MEDICAMENT (FR) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000058282-A2 | NOVEL [(2-SUBSTITUTED-5 -[3-THIENYL) -BENZYL]-[2- ([2-ISOPROPOXY-5-FLUORO] -PHENOXY) -ETHYL] -AMINE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | PIERRE FABRE MEDICAMENT (FR) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000032557-A1 | NOVEL 3-ALKOXYBENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICINES FOR TREATING SCHIZOPHRENIA | PIERRE FABRE MEDICAMENT (FR) | 2000-06-08 | — | — | WO | disclosed |