Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633474 | 0.94 | L3MBTL1 (0.63) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL10975718 | 0.93 | L3MBTL1 (0.55) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL17167936 | 0.90 | GNAI3 (0.65) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL22923584 | 0.90 | GNAI3 (0.65) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL31632752 | 0.90 | GNAI3 (0.65) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL31632758 | 0.90 | GNAI3 (0.65) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL10070849 | 0.86 | GNAI3 (0.60) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL12424660 | 0.86 | TSHR (0.54) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL8972823 | 0.86 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A | |
| SCHEMBL1045855 | 0.86 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | claimed |
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |