Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | GNAI3 | P08754 | 9/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633178 | 0.94 | GNAI3 (0.61) | L3MBTL1MEN1KMT2ATDP1GNAI3 | |
| SCHEMBL10975718 | 0.88 | L3MBTL1 (0.55) | L3MBTL1MEN1KMT2ATDP1GNAI3 | |
| SCHEMBL9634169 | 0.86 | L3MBTL1 (0.69) | L3MBTL1MEN1KMT2ATDP1GNAI3 | |
| SCHEMBL4554866 | 0.86 | L3MBTL1 (0.69) | L3MBTL1MEN1KMT2ATDP1GNAI3 | |
| SCHEMBL13290614 | 0.86 | L3MBTL1 (0.85) | L3MBTL1MEN1KMT2ATDP1GNAI3 | |
| SCHEMBL31632752 | 0.84 | GNAI3 (0.65) | L3MBTL1MEN1KMT2ATDP1GNAI3 | |
| SCHEMBL22923584 | 0.84 | GNAI3 (0.65) | L3MBTL1MEN1KMT2ATDP1GNAI3 | |
| SCHEMBL31632758 | 0.84 | GNAI3 (0.65) | L3MBTL1MEN1KMT2ATDP1GNAI3 | |
| SCHEMBL17167936 | 0.84 | GNAI3 (0.65) | L3MBTL1MEN1KMT2ATDP1GNAI3 | |
| SCHEMBL9762648 | 0.84 | L3MBTL1 (0.88) | L3MBTL1MEN1KMT2ATDP1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |