Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11963960 | 0.81 | CES2 (0.52) | PPARGPPARACES2CES1MAPT | |
| SCHEMBL10907716 | 0.81 | CES2 (0.52) | PPARGPPARACES2CES1MAPT | |
| SCHEMBL8686485 | 0.80 | PPARG (0.44) | PPARGPPARACES2CES1MAPT | |
| SCHEMBL11963974 | 0.80 | RAB9A (0.65) | PPARGPPARACES2CES1MAPT | |
| SCHEMBL29510116 | 0.79 | CASP3 (0.70) | CES2CES1MAPTALDH1A1CASP3 | |
| SCHEMBL10041971 | 0.79 | CASP3 (0.70) | CES2CES1MAPTALDH1A1CASP3 | |
| SCHEMBL8485793 | 0.79 | CASP3 (0.70) | CES2CES1MAPTALDH1A1CASP3 | |
| SCHEMBL8306489 | 0.79 | CASP3 (0.70) | CES2CES1MAPTALDH1A1CASP3 | |
| SCHEMBL8304592 | 0.78 | PPARG (0.58) | PPARGPPARACES2CES1MAPT | |
| SCHEMBL30098733 | 0.78 | PPARG (0.46) | PPARGPPARACES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145998-A | Reduction of oxime or silyloxime | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0237305-B1 | A METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | disclosed |