Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631291 | 0.82 | ALDH1A1 (0.48) | NR1H4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9533164 | 0.81 | TLR3 (0.48) | TLR3KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9632256 | 0.81 | TLR3 (0.46) | TLR3NR1H4KMT2ANPC1RAB9A | |
| SCHEMBL9531634 | 0.81 | TLR3 (0.47) | TLR3KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9630813 | 0.78 | TLR3 (0.40) | TLR3NR1H4KMT2ANPC1RAB9A | |
| SCHEMBL8194915 | 0.76 | KMT2A (0.39) | NR1H4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL10636214 | 0.74 | NR1H4 (0.41) | NR1H4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL10638787 | 0.72 | PPARG (0.45) | KMT2AMEN1MAPTALDH1A1CYP1A2 | |
| SCHEMBL8193430 | 0.70 | NR1H4 (0.38) | NR1H4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9531581 | 0.70 | TLR3 (0.41) | TLR3KMT2AMEN1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |