Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MPC2 | O95563 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630933 | 0.89 | MEN1 (0.47) | CYP3A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10636475 | 0.89 | MEN1 (0.48) | CYP3A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL5086147 | 0.84 | MEN1 (0.52) | CYP3A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10641818 | 0.83 | MEN1 (0.50) | CYP3A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10638986 | 0.83 | CYP3A4 (0.47) | CYP3A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9631318 | 0.83 | PSEN1 (0.46) | MEN1KMT2AMAPTTDP1PSEN1 | |
| SCHEMBL9631986 | 0.80 | TTPA (0.46) | MEN1KMT2AMAPTPSEN1PDE4A | |
| SCHEMBL9632317 | 0.80 | PSEN1 (0.40) | MEN1KMT2AMAPTTDP1PPARG | |
| SCHEMBL4727629 | 0.80 | MEN1 (0.52) | CYP3A4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10642035 | 0.79 | CYP3A4 (0.46) | CYP3A4MEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62005980-A | — | — | None | — | — | JP | disclosed |
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| JP-S625980-A | THIAZOLIDINE DERIVATIVE | SANKYO CO LTD | 1987-01-12 | — | — | JP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |