Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 3/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636293 | 0.90 | TTPA (0.49) | TTPAPSEN1KMT2AMEN1PDE4A | |
| SCHEMBL9631318 | 0.88 | PSEN1 (0.46) | TTPAPSEN1KMT2AMEN1PDE4A | |
| SCHEMBL9630985 | 0.88 | MAPT (0.43) | TTPAPSEN1KMT2AMEN1MGLL | |
| SCHEMBL9632130 | 0.87 | PSEN1 (0.44) | TTPAPSEN1KMT2AMEN1MGLL | |
| SCHEMBL10642037 | 0.85 | TTPA (0.47) | TTPAPSEN1KMT2AMEN1PDE4A | |
| SCHEMBL7536176 | 0.83 | TTPA (0.51) | TTPAPSEN1KMT2AMEN1PDE4A | |
| SCHEMBL9632317 | 0.82 | PSEN1 (0.40) | TTPAPSEN1KMT2AMEN1PDE4A | |
| SCHEMBL10373491 | 0.80 | TTPA (0.46) | TTPAPSEN1KMT2AMEN1PDE4A | |
| SCHEMBL9633318 | 0.80 | CYP3A4 (0.45) | PSEN1KMT2AMEN1PDE4APDE3A | |
| SCHEMBL10641788 | 0.80 | MEN1 (0.53) | TTPAPSEN1KMT2AMEN1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |