SCHEMBL9633489

SCHEMBL9633489

CCCC(O)c1c(C(N)=O)ccc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
WDR5 P61964 1/20 0.38
NCEH1 Q6PIU2 2/20 0.38
KDM4E B2RXH2 4/20 0.38
PARP1 P09874 1/20 0.38
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PARP15 Q460N3 1/20 0.38
PARP10 Q53GL7 1/20 0.38
RPS6KB1 P23443 1/20 0.37
ATM Q13315 1/20 0.37
LDHA P00338 1/20 0.37
ALDH1A1 P00352 3/20 0.37
GAA P10253 3/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PPARG P37231 2/20 0.37
PPARA Q07869 2/20 0.37
CNR1 P21554 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11017719 0.91 KMT2A (0.44) KMT2AMEN1NCEH1KDM4EPPARG
SCHEMBL7477120 0.79 NCEH1 (0.54) KMT2AMEN1WDR5NCEH1KDM4E
SCHEMBL241213 0.75 MEN1 (0.40) KMT2AMEN1KDM4EALDH1A1PPARG
SCHEMBL17592082 0.73 NCEH1 (0.52) KMT2AMEN1WDR5NCEH1KDM4E
SCHEMBL11594011 0.72 NCEH1 (0.50) KMT2AMEN1WDR5NCEH1KDM4E
SCHEMBL8189162 0.71 BCAT2 (0.40) KMT2AMEN1KDM4EALDH1A1
SCHEMBL29009407 0.71 NCEH1 (0.54) KMT2AMEN1WDR5NCEH1KDM4E
SCHEMBL28447076 0.70 KDM4E (0.45) KMT2AMEN1KDM4EPOLBSMN1; SMN2
SCHEMBL2000694 0.70 NPSR1 (0.40) KMT2AMEN1KDM4EPOLBSMN1; SMN2
SCHEMBL5153416 0.70 TSHR (0.50) KMT2AMEN1WDR5NCEH1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487084-A2 Image forming method and apparatus CANON KABUSHIKI KAISHA (JP) 1992-05-27 EP disclosed