Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 6/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.35 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.35 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.35 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.35 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.35 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185101 | 0.75 | BCAT2 (0.42) | BCAT2PLA2G2APLA2G10LTB4R2SLCO1B1 | |
| SCHEMBL9633489 | 0.71 | KMT2A (0.40) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4301679 | 0.70 | BCAT2 (0.57) | BCAT2KDM4EALDH1A1LTB4R2MEN1 | |
| SCHEMBL28360369 | 0.70 | PTGS1 (0.38) | KDM4EALDH1A1MEN1KMT2ADRD3 | |
| SCHEMBL28149292 | 0.66 | BCAT2 (0.50) | BCAT2PLA2G2APLA2G10KDM4ELTB4R2 | |
| SCHEMBL2377415 | 0.66 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL4444936 | 0.66 | BCAT2 (0.53) | BCAT2PLA2G2APLA2G10KDM4ELTB4R2 | |
| SCHEMBL29128772 | 0.65 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL3169510 | 0.64 | BCAT2 (0.51) | BCAT2PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL530128 | 0.64 | BCAT2 (0.56) | BCAT2PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080870-A | Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors | MERCK & CO., INC. (US) | 2000-06-27 | — | — | US | disclosed |