Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315108 | 0.84 | CHRM1 (0.35) | FFAR3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL10925798 | 0.82 | CA2 (0.38) | FFAR3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5188446 | 0.80 | CHRM1 (0.37) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28656014 | 0.79 | ALDH1A1 (0.37) | FFAR3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5219757 | 0.78 | CA2 (0.31) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1132194 | 0.78 | CA2 (0.35) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL11460745 | 0.77 | HSPD1 (0.33) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL12891264 | 0.76 | CA2 (0.41) | FFAR3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2631146 | 0.76 | CA2 (0.41) | FFAR3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL739847 | 0.76 | HSPD1 (0.37) | FFAR3CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162523-A | CEPHALOSPORIN ANTIBACTERIAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-5159077-A | Bactericide, antibiotic | HOFFMANN-LA ROCHE INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0409081-A1 | Beta-Lactam Derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-23 | — | — | EP | disclosed |