SCHEMBL9633668

SCHEMBL9633668

CCOC(C)CCC[C](C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.32
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3820500 0.78 GABRP (0.45)
SCHEMBL9632385 0.76
SCHEMBL216314 0.76
SCHEMBL2037324 0.76
SCHEMBL3315106 0.75
SCHEMBL460562 0.75 PAOX (0.42) LMNAFAAH
SCHEMBL9317960 0.74 LMNA (0.38) LMNATHRBFAAH
SCHEMBL18106104 0.73 OPRM1 (0.52) LMNATHRBFAAH
SCHEMBL610212 0.73 OPRM1 (0.52) LMNATHRBFAAH
SCHEMBL2737161 0.73 LMNA (0.43) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0276124-B1 PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE Sankyo Company Limited (JP) 1992-05-20 EP disclosed
US-4981872-A ANTIULCER SANKYO COMPANY LIMITED (JP) 1991-01-01 US disclosed