Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27163446 | 0.76 | OPRK1 (0.40) | KMT2AMEN1OPRK1KIF11SMN1; SMN2 | |
| SCHEMBL349483 | 0.75 | HSD11B1 (0.47) | KMT2AMEN1OPRK1KIF11SMN1; SMN2 | |
| SCHEMBL9633769 | 0.72 | MEN1 (0.50) | KMT2AMEN1KIF11SMN1; SMN2HPGD | |
| SCHEMBL28738251 | 0.72 | HSD11B1 (0.50) | OPRK1HPGDALDH1A1HSD17B10GAA | |
| SCHEMBL25167294 | 0.71 | OPRK1 (0.41) | KMT2AMEN1OPRK1KIF11HPGD | |
| SCHEMBL9631917 | 0.71 | HTT (0.40) | KMT2AKIF11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9631982 | 0.70 | OPRM1 (0.41) | KMT2AMEN1OPRK1SMN1; SMN2NPC1 | |
| SCHEMBL9631609 | 0.69 | KMT2A (0.45) | KMT2AMEN1KIF11NPC1RAB9A | |
| SCHEMBL26451965 | 0.68 | HSD17B10 (0.39) | OPRK1SMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL14341359 | 0.67 | HSD11B1 (0.40) | KMT2AOPRK1KIF11SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120861-A | DIAZIRINE DERIVATIVES OF AROMATIC HETEROCYCLIC COMPOUNDS | SHELL RESEARCH LIMITED (GB) | 1992-06-09 | — | — | US | disclosed |
| EP-0432817-A1 | Diazirine derivatives of aromatic heterocyclic compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-06-19 | — | — | EP | disclosed |