Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134251 | 0.76 | EHMT2 (0.61) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30548750 | 0.76 | EHMT2 (0.61) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL6699101 | 0.74 | L3MBTL1 (0.56) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL2894246 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTAPLNRALOX15 | |
| SCHEMBL301719 | 0.70 | EHMT2 (0.70) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL28766794 | 0.70 | ALDH1A1 (0.47) | ALDH1A1HPGDAPLNRALOX15HSD17B10 | |
| SCHEMBL10423274 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL1457530 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30940598 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL4439023 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298915-B1 | PYRIDYLTHIO-, PYRIDYLSULFINYL- AND PYRIDYLSULFONYL-PHENYL-THIOUREAS, ISOTHIOUREAS AND CARBON DIIMIDES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1992-05-20 | — | — | EP | disclosed |
| EP-0298915-A1 | Pyridylthio-, pyridylsulfinyl- and pyridylsulfonyl-phenyl-thioureas, isothioureas and carbon diimides, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1989-01-11 | — | — | EP | disclosed |