Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727216 | 0.98 | CA1 (0.47) | FDPSCA1SMPD1ACE2ZDHHC7 | |
| SCHEMBL11720011 | 0.98 | CA1 (0.47) | FDPSCA1SMPD1ACE2ZDHHC7 | |
| SCHEMBL11316721 | 0.93 | FDPS (0.42) | FDPSCA1SMPD1PLA2G2ACA2 | |
| SCHEMBL11315637 | 0.93 | FDPS (0.42) | FDPSCA1SMPD1PLA2G2ACA2 | |
| SCHEMBL7941316 | 0.93 | FDPS (0.42) | FDPSCA1SMPD1PLA2G2ACA2 | |
| SCHEMBL11851600 | 0.86 | FDPS (0.39) | FDPSCA1CA2 | |
| SCHEMBL11863469 | 0.83 | MAPT (0.53) | FDPSSMPD1ZDHHC7PLA2G2ALAP3 | |
| SCHEMBL9160566 | 0.81 | MAPT (0.50) | FDPSSMPD1ZDHHC7PLA2G2ALAP3 | |
| SCHEMBL11460321 | 0.79 | — | — | |
| SCHEMBL12951695 | 0.78 | MMP1 (0.35) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276124-B1 | PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-4981872-A | ANTIULCER | SANKYO COMPANY LIMITED (JP) | 1991-01-01 | — | — | US | disclosed |
| US-3987072-A | CIS-4,5-Didehydro-15- or 16-alkylated 11-deoxy-PGE1 analogs | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |