Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11316721 | 1.00 | FDPS (0.42) | FDPSCA2CA1MAPK1SMPD1 | |
| SCHEMBL11315637 | 1.00 | FDPS (0.42) | FDPSCA2CA1MAPK1SMPD1 | |
| SCHEMBL10727216 | 0.95 | CA1 (0.47) | FDPSCA2CA1SMPD1PLA2G2A | |
| SCHEMBL11720011 | 0.95 | CA1 (0.47) | FDPSCA2CA1SMPD1PLA2G2A | |
| SCHEMBL9633958 | 0.93 | FDPS (0.46) | FDPSCA2CA1SMPD1PLA2G2A | |
| SCHEMBL11851600 | 0.89 | FDPS (0.39) | FDPSCA2CA1 | |
| SCHEMBL11493233 | 0.84 | CA2 (0.53) | FDPSCA2CA1MAPK1 | |
| SCHEMBL11094123 | 0.82 | FDPS (0.38) | FDPSCA2CA1MAPK1SMPD1 | |
| SCHEMBL13852716 | 0.82 | GPR84 (0.40) | FDPSCA2CA1SMPD1PLA2G2A | |
| SCHEMBL11460321 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265440-B1 | STOMACH ULCERS | R-TECH UENO, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-5428062-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5401768-A | Prostaglandin derivative, antiulcer, hypotensive, anticoagulant | TORAY INDUSTRIES, INC. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0365678-B1 | 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF | TORAY INDUSTRIES (JP) | 1994-01-05 | — | — | EP | disclosed |
| EP-0389162-B1 | 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES (JP) | 1993-12-08 | — | — | EP | disclosed |
| EP-0240890-B1 | Prostacyclin (PGI2) analogues | SHIONOGI & CO (JP) | 1993-11-18 | — | — | EP | disclosed |
| EP-0276124-B1 | PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-5086071-A | Improved chemical stability and ppotent in vivo | TORAY INDUSTRIES, INC. (JP) | 1992-02-04 | — | — | US | disclosed |
| EP-0232776-B1 | 2,5,6,7-TETRANOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1990-10-24 | — | — | EP | disclosed |
| EP-0207598-B1 | PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4084063-A | PROSTAGLANDINS; ANTIULCER AGENTS, ANTICOAGULANTS, OXYTOCICS, DECONGESTANTS | THE UPJOHN COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-4035392-A | Prostanoic acid intermediate | CARLO ERBA S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |
| US-4035414-A | Prostanoic acid derivatives | CARLO ERBA S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |
| US-4021477-A | 14-Chloro prostadienoic acid compounds | CARLO-ERBA S.P.A. (IT) | 1977-05-03 | — | — | US | disclosed |
| US-3987085-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3969396-A | 8β, 11β, 12α-PGE2 compounds | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3954833-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3935254-A | 5C-PROSTEN-13-YNOIC ACIDS | CARLO ERBA S.P.A. (IT) | 1976-01-27 | — | — | US | disclosed |
| US-3933889-A | 4,5-Cis-didehydro-PGF1.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |