SCHEMBL9634073

SCHEMBL9634073

CC(=O)Oc1ccc([P+](C)(c2ccccc2)c2ccccc2)cc1.Cc1ccc(S(=O)(=O)[O-])cc1O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
POLB P06746 2/20 0.43
PKM P14618 1/20 0.43
ALDH1A1 P00352 2/20 0.42
KMT2A Q03164 2/20 0.40
ELANE P08246 2/20 0.39
MEN1 O00255 1/20 0.38
PTGS2 P35354 2/20 0.38
GAA P10253 2/20 0.37
HSP90AA1 P07900 1/20 0.37
LMNA P02545 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 2/20 0.37
ACHE P22303 1/20 0.36
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PKLR P30613 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634057 0.87 GAA (0.45) MAPTPOLBPKMALDH1A1KMT2A
SCHEMBL9635307 0.87 LMNA (0.46) MAPTPOLBALDH1A1KMT2AGAA
SCHEMBL9634069 0.84 ALDH1A1 (0.55) MAPTPOLBPKMALDH1A1KMT2A
SCHEMBL9633444 0.84 ALDH1A1 (0.55) MAPTPOLBPKMALDH1A1KMT2A
SCHEMBL9634065 0.82 CA12 (0.41) POLBPKMALDH1A1PTGS2GAA
SCHEMBL8374168 0.80 POLB (0.41) MAPTPOLBPKMALDH1A1KMT2A
SCHEMBL8378039 0.80 POLB (0.41) MAPTPOLBPKMALDH1A1KMT2A
SCHEMBL9635318 0.79 LMNA (0.57) MAPTPOLBPKMALDH1A1KMT2A
SCHEMBL8378603 0.76 ELANE (0.53) MAPTPOLBPKMALDH1A1KMT2A
SCHEMBL8378062 0.74 MAPT (0.44) MAPTPOLBPKMALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315082-B1 PROCESS FOR INCREASING THE ELECTROSTATIC CHARGEABILITY OF POWDER PAINTS OR POWDERS AND THEIR USE IN THE SURFACE COATING OF SOLID ITEMS HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-06 EP disclosed
EP-0315082-A2 Process for increasing the electrostatic chargeability of powder paints or powders and their use in the surface coating of solid items HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-10 EP disclosed