Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686241 | 0.94 | ALDH1A1 (0.42) | ALDH1A1TDP1LMNATSHRCYP3A4 | |
| SCHEMBL17674241 | 0.92 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNATSHRCYP3A4 | |
| SCHEMBL8464662 | 0.92 | LMNA (0.46) | ALDH1A1TDP1LMNATSHRCYP3A4 | |
| SCHEMBL8838785 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TDP1LMNATSHRCYP3A4 | |
| SCHEMBL3397923 | 0.88 | TSHR (0.50) | ALDH1A1TDP1LMNATSHRCYP3A4 | |
| SCHEMBL6154186 | 0.81 | TSHR (0.52) | ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL16295209 | 0.80 | LMNA (0.43) | ALDH1A1TDP1LMNATSHRCYP3A4 | |
| SCHEMBL9092266 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TDP1LMNATSHRCYP3A4 | |
| SCHEMBL3689153 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TDP1LMNATSHRCYP3A4 | |
| SCHEMBL20746322 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TDP1LMNATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162016-B1 | ADDITIVES FOR MATERIALS | CIBA-GEIGY AG (CH) | 1992-06-03 | — | — | EP | claimed |
| US-4737300-A | LUBRICANTS, STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | claimed |
| EP-0162016-B1 | ADDITIVES FOR MATERIALS | CIBA-GEIGY AG (CH) | 1992-06-03 | — | — | EP | disclosed |
| US-4737300-A | LUBRICANTS, STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | disclosed |
| EP-0162016-A2 | Additives for materials | CIBA-GEIGY AG (CH) | 1985-11-21 | — | — | EP | disclosed |