Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397923 | 0.93 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL9634110 | 0.81 | ALDH1A1 (0.43) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL1579602 | 0.80 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL8838785 | 0.80 | ALDH1A1 (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL10686241 | 0.79 | ALDH1A1 (0.42) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL545145 | 0.78 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL17674241 | 0.77 | ALDH1A1 (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL1634535 | 0.76 | TSHR (0.56) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL4804369 | 0.76 | TSHR (0.56) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL8464662 | 0.76 | LMNA (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256226-A1 | Phosphate esters dispersants | LUBRIZOL CORPORATION, THE | 2005-11-17 | — | — | US | disclosed |
| EP-1499655-A1 | PHOSPHATE ESTERS DISPERSANTS | Lubrizol Limited (GB) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003072632-A1 | PHOSPHATE ESTERS DISPERSANTS | THE LUBRIZOL CORPORATION (US) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256226-A1 | Phosphate esters dispersants | PHOSPHO1, PHPT1, PPIP5K2 | TSHR 2050/4885SMN1; SMN2 4660/4885ALDH1A1 3224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.