Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636115 | 1.00 | MAOB (0.48) | MAOBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL10845975 | 0.91 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EMAPTS1PR1 | |
| SCHEMBL9634345 | 0.90 | KDM4E (0.60) | MAOBALDH1A1HPGDKDM4ETOP1 | |
| SCHEMBL9634508 | 0.90 | KDM4E (0.60) | MAOBALDH1A1HPGDKDM4ETOP1 | |
| Hydrochloric Acid SCHEMBL10847302 | 0.90 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EMAPTS1PR1 | |
| SCHEMBL9634312 | 0.88 | KDM4E (0.41) | MAOBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9635537 | 0.87 | ALDH1A1 (0.43) | MAOBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9634834 | 0.85 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ETOP1TOP2A | |
| SCHEMBL9636238 | 0.83 | MAPT (0.43) | MAOBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9634938 | 0.83 | PDE10A (0.40) | MAOBALDH1A1PDE10AKMT2AGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104881-A | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-04-14 | — | — | US | disclosed |
| US-4616090-A | 2-arylimidazopyridines intermediates | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0072926-B1 | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GmbH (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0072926-A1 | 2-Arylimidazopyridines | MERCK PATENT GmbH (DE) | 1983-03-02 | — | — | EP | disclosed |