Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634345 | 0.96 | KDM4E (0.60) | KDM4EALDH1A1HPGDALOX5EPHX2 | |
| SCHEMBL9636115 | 0.90 | MAOB (0.48) | KDM4EALDH1A1HPGDMAOBMAOA | |
| SCHEMBL9634280 | 0.90 | MAOB (0.48) | KDM4EALDH1A1HPGDMAOBMAOA | |
| SCHEMBL9635815 | 0.88 | KDM4E (0.49) | KDM4EALDH1A1HPGDALOX5EPHX2 | |
| SCHEMBL7271604 | 0.86 | KDM4E (0.78) | KDM4EALDH1A1HPGDALOX5EPHX2 | |
| SCHEMBL9634834 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDEPHX2GUSB | |
| SCHEMBL9635537 | 0.85 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDALOX5EPHX2 | |
| Hydrochloric Acid SCHEMBL10846499 | 0.85 | KDM4E (0.81) | KDM4EALDH1A1HPGDALOX5EPHX2 | |
| Hydrochloric Acid SCHEMBL7271989 | 0.85 | KDM4E (0.81) | KDM4EALDH1A1HPGDALOX5EPHX2 | |
| SCHEMBL10737750 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1HPGDALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104881-A | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-04-14 | — | — | US | disclosed |
| US-4616090-A | 2-arylimidazopyridines intermediates | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0072926-B1 | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GmbH (DE) | 1986-09-24 | — | — | EP | disclosed |