Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 4/20 | 0.37 |
| ▸ | CDK8 | P49336 | 4/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966303 | 0.90 | CCNC (0.38) | CCNCCDK8NPC1RAB9ACNKSR1 | |
| SCHEMBL967738 | 0.89 | ALDH1A1 (0.41) | CCNCCDK8NPC1RAB9ATTR | |
| SCHEMBL964973 | 0.89 | XPO1 (0.38) | CCNCCDK8NPC1RAB9ATTR | |
| SCHEMBL965036 | 0.87 | ALDH1A1 (0.44) | CCNCCDK8ENPP3ENPP1NPC1 | |
| SCHEMBL965034 | 0.87 | ALDH1A1 (0.44) | CCNCCDK8ENPP3ENPP1NPC1 | |
| SCHEMBL962983 | 0.86 | POLB (0.42) | CCNCCDK8DPP4ALDH1A1HPGD | |
| SCHEMBL962300 | 0.83 | LMNA (0.38) | CCNCCDK8ENPP3NPC1RAB9A | |
| SCHEMBL964262 | 0.81 | ENPP3 (0.38) | ENPP3ENPP1FGFR1FGFR4 | |
| SCHEMBL964264 | 0.81 | ENPP3 (0.38) | ENPP3ENPP1FGFR1FGFR4 | |
| SCHEMBL963124 | 0.81 | ENPP3 (0.39) | ENPP3ENPP1FGFR1FGFR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | PPARA, PPARD, PPARG | CCNC 3591/4885CDK8 2477/4885ENPP3 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.