Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | POLB | P06746 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 5/20 | 0.60 |
| ▸ | ACHE | P22303 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.60 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.60 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.60 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.60 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.60 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363298 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| Water SCHEMBL3871916 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL30861620 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL22208005 | 0.85 | ALDH1A1 (0.68) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL6892551 | 0.84 | POLB (0.72) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL30861636 | 0.84 | POLB (0.72) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL12850775 | 0.82 | POLB (0.72) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL28757725 | 0.81 | POLB (0.69) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL22224161 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL22207995 | 0.78 | HSD17B10 (0.73) | ALDH1A1KDM4EPOLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019016269-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2019-01-24 | — | — | WO | disclosed |
| EP-0485419-A1 | ACRIDINE DERIVATIVES | Trifree Limited (GB) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991001974-A1 | ACRIDINE DERIVATIVES | TRIFREE LIMITED (GB) | 1991-02-21 | — | — | WO | disclosed |