Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38901 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10ALOX12ALOX15 | |
| Benzene SCHEMBL27879268 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10ALOX12ALOX15 | |
| Benzene SCHEMBL28223369 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10ALOX12ALOX15 | |
| SCHEMBL1778033 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10ALOX12TDP1 | |
| Ammonia Solution, Strong SCHEMBL28239369 | 0.69 | TSHR (0.37) | ALDH1A1ALOX12TDP1TSHRCA1 | |
| Phosphine SCHEMBL29078666 | 0.67 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10ALOX12ALOX15 | |
| Fluoride SCHEMBL28572273 | 0.67 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10ALOX12ALOX15 | |
| SCHEMBL21838773 | 0.67 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10ALOX12ALOX15 | |
| SCHEMBL28546150 | 0.67 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10ALOX12ALOX15 | |
| Hydrochloric Acid SCHEMBL6905007 | 0.67 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10ALOX12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175331-A | Reacting silicon tetrafluoride with alkyl or aryl halide in presence of metallic aluminum catalyst; chlorination, bromination or iodination | ETHYL CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5138082-A | Catalytic reaction of silicon tetrafluoride with organo-aluminum compound | ETHYL CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |