Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634895 | 0.88 | THRB (0.31) | THRBPOLB | |
| SCHEMBL6267054 | 0.87 | GABRP (0.31) | THRBALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL28181726 | 0.85 | THRB (0.31) | THRBPOLB | |
| SCHEMBL10579255 | 0.82 | TSHR (0.35) | THRBTSHRHPGD | |
| SCHEMBL29159220 | 0.80 | THRB (0.35) | THRBTSHRALDH1A1HPGDKDM4E | |
| SCHEMBL10390175 | 0.79 | TSHR (0.33) | THRBTSHRHPGD | |
| SCHEMBL28218280 | 0.79 | GRM1 (0.33) | THRBPOLBSLC22A6SLC22A8 | |
| SCHEMBL6267057 | 0.78 | GABRP (0.31) | THRBALDH1A1POLBMEN1RECQL | |
| SCHEMBL1371364 | 0.78 | THRB (0.41) | THRBALDH1A1POLBTHRAMEN1 | |
| SCHEMBL23121518 | 0.77 | SLC37A4 (0.43) | THRBALDH1A1POLBHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122436-A | Homogeneous blend of polyimidesiloxane and unsaturated monomer | EASTMAN KODAK COMPANY (US) | 1992-06-16 | — | — | US | disclosed |
| US-5098814-A | Integrated circuit chips of laminates of flexible metal strips and photoresists of polyimidesiloxane copolymers | EASTMAN KODAK COMPANY (US) | 1992-03-24 | — | — | US | disclosed |