Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635973 | 0.84 | KMT2A (0.47) | TSHRALDH1A1SMN1; SMN2PKMCYP19A1 | |
| SCHEMBL9192086 | 0.77 | KAT2B (0.59) | TSHRALDH1A1SMN1; SMN2PKMNT5E | |
| SCHEMBL10694484 | 0.74 | ALDH1A1 (0.44) | TSHRTDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL10603180 | 0.73 | ALDH1A1 (0.58) | TSHRALDH1A1SMN1; SMN2PKMCYP19A1 | |
| SCHEMBL10851653 | 0.73 | KMT2A (0.60) | TSHRTDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL9878203 | 0.73 | ALDH1A1 (0.50) | TSHRTDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL9878201 | 0.72 | KAT2B (0.46) | TSHRTDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL11111278 | 0.71 | ALDH1A1 (0.50) | TSHRTDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL10597376 | 0.70 | KMT2A (0.45) | TSHRTDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL10597296 | 0.70 | POLB (0.45) | TSHRTDP1ALDH1A1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171852-A | Dye cellulose textiles bright reddish blue shades | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |
| EP-0279122-B1 | REACTIVE DYES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-10 | — | — | EP | disclosed |
| EP-0279122-A2 | Reactive dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | disclosed |