Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877927 | 0.89 | KMT2A (0.54) | ALDH1A1SMN1; SMN2POLBCYP19A1KMT2A | |
| SCHEMBL9877903 | 0.87 | ALDH1A1 (0.59) | KAT2BALDH1A1SMN1; SMN2POLBCYP19A1 | |
| SCHEMBL10597296 | 0.86 | POLB (0.45) | KAT2BALDH1A1SMN1; SMN2POLBCYP19A1 | |
| SCHEMBL9878286 | 0.84 | MAPT (0.60) | ALDH1A1SMN1; SMN2POLBCYP19A1KMT2A | |
| SCHEMBL9879008 | 0.81 | CYP19A1 (0.42) | ALDH1A1SMN1; SMN2POLBCYP19A1KMT2A | |
| SCHEMBL9878800 | 0.81 | RAPGEF4 (0.38) | ALDH1A1POLBKMT2ATDP1GAA | |
| SCHEMBL9877920 | 0.81 | CYP19A1 (0.44) | ALDH1A1SMN1; SMN2POLBCYP19A1TDP1 | |
| SCHEMBL9878326 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBKMT2ATDP1 | |
| SCHEMBL9878203 | 0.79 | ALDH1A1 (0.50) | KAT2BALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL10694484 | 0.78 | ALDH1A1 (0.44) | KAT2BALDH1A1SMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |